While Barbara George scored one of New Orleans’ biggest hits “I Know (You Don’t Love Me No More),” which in 1961 rose to No. 3 in the pop charts and topped the R&B charts, her career nonetheless was one of squandered promise. Sadly, poor business and personal decisions would render her near the top of the “One Hit Wonders” list.

Barbara George was born August 16, 1942. Producer and label owner Harold Battiste recalls she grew up in the notorious Desire Pr...